He was born in Rome on April 13, 1850. In 1862, he met the Hungarian pianist and composer Franz Liszt, with whom he began studying piano. At the age of sixteen, he traveled to study harmony and counterpoint at the Munich Conservatory, where he was taught by Hans von Bülow. Shortly after, and starting in 1869, he performed his first concerts in various European cities, beginning a series of tours throughout Europe and America in 1873.

In 1885 he arrived in Montevideo as part of one of his tours. In one of the concerts he gave, he met the pianist Luisa Gallo, whom he married that same year. Together, they founded the Franz Liszt Conservatory of Music in 1895, which became a leading center for music instruction in the country. That same year, he founded the Sociedad Coral Santa Cecilia (Santa Cecilia Choral Society), dedicated to religious music.

Camilo and Luisa had nine children, two of whom died at an early age. Camilo, Luisa, Mario, Carlos, and Esther were involved in various ways to music creation and instruction.

Camilo composed a series of works for piano, some of which were premiered in Europe, while others correspond to the period in which he lived in Uruguay

Camilo Giucci died on December 5, 1913.